25-hydroxyvitamin D status and change in physical performance and strength in older adults: the Health, Aging, and Body Composition Study.
نویسندگان
چکیده
Low 25-hydroxyvitamin D (25(OH)D) concentrations are common among older adults and are associated with poorer physical performance and strength, but results from longitudinal studies have been inconsistent. The 25(OH)D threshold for physical performance and strength was determined, and both cross-sectional and longitudinal associations between 25(OH)D and physical performance and strength were examined, in men and women aged 71-80 years from the Health, Aging, and Body Composition Study (n = 2,641). Baseline serum 25(OH)D was measured in 1998-1999, and physical performance and strength were measured at baseline and at 2- and 4-year follow-up. Piecewise regression models were used to determine 25(OH)D thresholds. Linear regression and mixed models were used to examine cross-sectional and longitudinal associations. The 25(OH)D thresholds were 70-80 nmol/L for physical performance and 55-70 nmol/L for strength. Participants with 25(OH)D <50 nmol/L had poorer physical performance at baseline and at 2- and 4-year follow-up than participants with 25(OH)D ≥75 nmol/L (P < 0.01). Although physical performance and strength declined over 4 years of follow-up (P < 0.0001), in general, the rate of decline was not associated with baseline 25(OH)D. Older adults with low 25(OH)D concentrations had poorer physical performance over 4 years of follow-up, but low 25(OH)D concentrations were not associated with a faster rate of decline in physical performance or strength.
منابع مشابه
ASSESSMENT OF PHYSICAL FUNCTIONING AND ITS CORRELATES IN ADULTS 50 YEARS AND OLDER IN BUKAN, NORTHWEST OF IRAN; A CROSS-SECTIONAL STUDY
Background & Aims: Aging is associated with gradual erosive changes in the physiological function of many systems of the body. Ths study aimed to examine the physical functioning and limitation and its related factors in people aged 50 and older in Bukan, 2017. Materials & Methods: In this cross-sectional study 1201 elderly people aged 50 years and up were recruited from health recentres in Bu...
متن کاملPrevalence and Correlates of Functional Disability among Community-Dwelling Older Adults in India: Results of a National Survey in 2017-2019
Introduction: Aging may increase physical or functional limitations, and India has a rapidly aging population. This study aimed to assess the prevalence and correlates of difficulties with Activities of Daily Living (ADL) and Instrumental Activities of Daily Living (IADL) among older adults in India. Methods: The cross-sectional sample consisted of 31,477 individuals (≥ 60 years) from the Long...
متن کاملEffect of Vitamin D Supplement Consumption on Muscle Strength, Muscle Function and Body Composition in Vitamin D-deficient Middle-aged Women: A Randomized Clinical Trial
Background and Objectives: Sarcopenia is explained as the loss of muscle strength and muscle mass with aging‚ and is one of the major risk factors for metabolic diseases. Cross-sectional studies demonstrate that vitamin D is associated with sarcopenia in both men and women. The aim of this study was to investigate the effect of vitamin D supplement consumption on muscle strength, muscle f...
متن کاملThe relationship between serum 25-hydroxy vitamin D and blood pressure and quality of life in overweight and obese patients with type 2 diabetes mellitus compared with healthy subjects
Background: Vitamin D is one of the known lipoprotein hormones with metabolic properties. We aimed to determine the serum 25-hydroxy vitamin D concentration in overweight/obese subjects with diabetes mellitus type Ⅱ (DM Ⅱ) in association with systolic and diastolic blood pressure and quality of life compared with healthy participants. Methods: The current case-control study was carried out amo...
متن کاملThe Relationship Between Demographic, Health, Physical Fitness and Socioeconomic Determinants and Functional Performance of Elderly People
Purpose: Increased life expectancy leads to an increase in the elderly population. However, with an increase in the age, the number of chronic diseases and cognitive disorders also increases. Since the social, cultural, environmental, lifestyle and health-related behavior is specific to each nation, the present study aimed at investigating the relationship between socio-economic status, health,...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- American journal of epidemiology
دوره 176 11 شماره
صفحات -
تاریخ انتشار 2012